Neurology
Neurology R&D
Multiple sclerosis (MS) is a chronic, immune-mediated, neurodegenerative disease

The estimated adult population diagnosed with MS is ~800,000 persons1-3
Inflammation and demyelination in the CNS lead to:
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Irreversible axonal loss
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Cognitive dysfunction
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Brain volume loss
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Long-term disability
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CNS, central nervous system; FDA, US Food and Drug Administration.
References: 1. S0101: Age and sex 2023 American Community Survey 1-year estimates. US Census Bureau. Accessed June 10, 2025. https://data.census.gov/table/ACSST1Y2023.S0101?q=United 2. Wallin MT, Culpepper WJ, Campbell JD, et al. The prevalence of MS in the United States: a population-based estimate using health claims data. Neurology. 2019;92(10):e1029-e1040. doi:10.1212/WNL.0000000000007035 3. Data on file. Sanofi US.
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